Browsing by Author "Yilmaz, Meral"
Now showing items 1-12 of 12
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Aldosterone Synthase CYP11B2 Gene Promoter Polymorphism in a Turkish Population With Chronic Kidney Disease
Yilmaz, Meral; Sari, Ismail; Bagci, Binnur; Gumus, Erkan; Ozdemir, Ozturk (IRANIAN SOC NEPHROLGY, 2015)Introduction. It has been shown that gene polymorphisms influence the development and progression of chronic kidney disease (CKD). Many studies have indicated that aldosterone synthase CYP11B2 gene polymorphism (-344C>T) ... -
Association of microsomal epoxide hydrolase gene polymorphism and pre-eclampsia in Turkish women
Pinarbasi, Ergun; Percin, Ferda E.; Yilmaz, Meral; Akgun, Egemen; Cetin, Meral; Cetin, Ali (WILEY, 2007)Aim: To assess the association between human epoxide hydrolase exon 3 and 4 polymorphisms and pre-eclampsia by carrying out a case-control study in Turkish women. Methods: DNA was extracted from peripheral blood leukocytes, ... -
The Association of MYNN and TERC Gene Polymorphisms and Bladder Cancer in a Turkish Population
Polat, Fikriye; Yilmaz, Meral; Diler, Songul Budak (UROL & NEPHROL RES CTR-UNRC, 2019)Purpose: Researchers reported that, MYNN rs10936599 polymorphism is in strong or moderate linkage disequilibrium with SNPs within the 3q26.2 chromosomal regions that also include the TERC gene. In addition, it has been ... -
Effect of tumour necrosis factor-alpha and interleukin-6 promoter polymorphisms on course of Crimean-Congo hemorrhagic fever in Turkish patients
Yilmaz, Meral; Elaldi, Nazif; Bagci, Binnur; Sari, Ismail; Gumus, Erkan; Yelkovan, Izzet (WOLTERS KLUWER MEDKNOW PUBLICATIONS, 2015)Objective: In this case-control study, we investigated whether IL-6 (-174G/C) and TNF-alpha (-308G/A) gene polymorphisms affect the clinical course and outcome of CCHF. Methods: Total 150 patients with CCHF and 170 controls ... -
Effects of vitrification and transplantation on follicular development and expression of EphrinB1 and PDGFA in mouse ovaries
Gumus, Erkan; Kaloglu, Celal; Sari, Ismail; Yilmaz, Meral; Cetin, Ali (ACADEMIC PRESS INC ELSEVIER SCIENCE, 2018)The aim of this study was to assess the follicular development and the patterns of EphrinB1 and PDGFA immunostaining in vitrified mouse ovarian tissue (OT) with and without transplantation. Histological evaluation was ... -
eNOS gene polymorphisms in paraffin-embedded tissues of prostate cancer patients
Polat, Fikriye; Turaclar, Nesrin; Yilmaz, Meral; Bingol, Gunsel; Cingilli Vural, Hasibe (TUBITAK SCIENTIFIC & TECHNICAL RESEARCH COUNCIL TURKEY, 2016)Background/aim: The purpose of the present study was to investigate whether endothelial nitric oxide synthase (eNOS) gene polymorphisms play a role in prostate cancer (PCa). Materials and methods: We examined three eNOS ... -
Investigation of LAMTOR1 gene and protein expressions in germinal vesicle and metaphase II oocytes and embryos from 1-cell to blastocyst stage in a mouse model
Gumus, Erkan; Sari, Ismail; Yilmaz, Meral; Cetin, Ali (ELSEVIER SCIENCE BV, 2018)Improving the success of in vitro fertilization (IVF) and infertility treatment depend on understanding basic cellular and molecular mechanisms of human preimplantation development. Pre-implantation mouse embryo model is ... -
Is there a relation between Murine double minute 2 T309G polymorphism and lung cancer risk in the Turkish population?
Yilmaz, Meral; Tas, Ayca; Kacan, Turgut; Sari, Musa; Silig, Yavuz (WALTER DE GRUYTER GMBH, 2017)Introduction: Association between Murine double minute 2 T309G polymorphism and lung cancer risk has been investigated in several populations, but results of these studies are inconsistent. We aimed to investigate the ... -
Lack of Association between the MTHFR C677T Polymorphism and Lung Cancer in a Turkish Population
Yilmaz, Meral; Kacan, Turgut; Sari, Ismail; Kilickap, Saadettin (ASIAN PACIFIC ORGANIZATION CANCER PREVENTION, 2014)Background: In this case-control study, we aimed to investigate the relationship between the methylenetetrahydrofolate reductase (MTHFR) C677T polymorphism and lung cancer. Materials and Methods: Total 200 individuals ... -
Relationship between IFNA1, IFNA5, IFNA10, and IFNA17 gene polymorphisms and Crimean-Congo hemorrhagic fever prognosis in a Turkish population range
Elaldi, Nazif; Yilmaz, Meral; Bagci, Binnur; Yelkovan, Izzet; Bagci, Gokhan; Gozel, Mustafa Gokhan; Engin, Aynur; Bakir, Mehmet; Dokmetas, Ilyas (WILEY, 2016)Crimean-Congo hemorrhagic fever (CCHF) is a fatal emerging acute viral infection. Not much is known regarding the pathogenic mechanisms and the reasons behind severe or mild disease courses in CCHF. IFN-alpha (IFNA) is one ... -
Sequential determination of serum viral titers, virus-specific IgG antibodies, and TNF-alpha, IL-6, IL-10, and IFN-gamma levels in patients with Crimean-Congo hemorrhagic fever
Kaya, Safak; Elaldi, Nazif; Kubar, Ayhan; Gursoy, Nevcihan; Yilmaz, Meral; Karakus, Gulderen; Gunes, Turabi; Polat, Zubeyde; Gozel, Mustafa Gokhan; Engin, Aynur; Dokmetas, Ilyas; Bakir, Mehmet; Yilmaz, Neziha; Sencan, Mehmet (BIOMED CENTRAL LTD, 2014)Background: Although there have been a number of studies on the pathogenesis of Crimean-Congo hemorrhagic fever (CCHF) recently, knowledge on this topic is still insufficient. This study aims to reveal the kinetics of serum ... -
Significant Association Between Polymorphisms of Wnt Antagonist Genes and Lung Cancer
Yilmaz, Meral; Donmez, Gonca; Kacan, Turgut; Sari, Ismail; Babacan, Nalan Akgul; Sari, Musa; Kilickap, Saadettin (BMJ PUBLISHING GROUP, 2015)Further elucidation of the molecular mechanisms underlying lung cancer (LC) is essential for the development of new effective therapeutic agents. Recently, involvement of Wnt antagonists in oncogenesis has been demonstrated ...